Scientists Print First 3D Heart Using Patient’s Biological Materials.

Scientists Print First 3D Heart Using Patient’s Biological Materials.

April 19, 2019.

Today is the World of science and technology. Day by day, new kind of inventions are coming into light in the medical field. Two scientists at the Tel Aviv University succeed to print the first ever 3D heart using the patient’s own cells, which they say could be used to patch diseased hearts or eventually be used for transplant. They produced an entire heart, complete with cells, blood vessels, ventricles, and chambers while in the past time scientists could manage to print a heart with only simple tissues without vessels.

To create the 3D printed heart, scientists started with a biopsy of fatty tissue taken from patients. The cellular material from the tissues was used as the bionic ink for the printer. To do this, they separated the cellular material from the tissues and reprogrammed it to become pluripotent stem cells. The extracellular matrix (a three-dimensional network of extracellular macromolecules such as collagen and glycoproteins) were processed into a personalized hydrogel.

Prof Tal Dvir of Tel Aviv University’s School of Molecular Cell Biology and Biotechnology, Department of Materials Science and Engineering, Center for Nanoscience and Nanotechnology and Sagol Center for Regenerative Biotechnology, who led the research for the study says, “This is the first time anyone anywhere has successfully engineered and printed an entire heart replete with cells, blood vessels, ventricles, and chambers.”

Two scientists, Prof Dvir, Dr. Assaf Shapira of TAU’s Faculty of Life Sciences and Nadav Moor, a doctoral student in Prof Dvir’s lab jointly conducted the research for the study. The technology can eventually lead to the production of a human-sized organ, whether, the human heart they printed is of the size of a rabbit’s heart.

Prof Dvir explains, ” Larger human heart requires the same technology” however, ” At this stage, our 3D heart is small, the size of a rabbit’s heart.”

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